Effects of Broccoli Extract (Brassica oleracea var. italica) on Collagen Images in Wounds: Experimental Study in Wistar Rats (Rattus norvegicus)

ABSTRACTIntroduction: Wound healing is a protective function of the body that focuses on quick recovery where regeneration process in hostile environment takes more time. In particular, oral cavity remarkable which wound occurs warm fluid contains millions microorganisms. Collagen plays an important role all phases healing, provides integrity and strength to tissues it very especially proliferation remodeling phases. One materials have potential related collagen broccoli (Brassica oleracea var.italica). Broccoli has regulate collagen, therefore could be alternative answer problem antiinflammatory, antioxidant, antimicrobial effects. The aim this research with experimental design study effects extract representation image wounds.Methods: This used 18 male wistar rats by making incision each rats’ back. These are divided into two groups, control group get no treatment, treatment treated applying topically twice day. observed microscopically 3th, 7th, 14th density fibers was measured based calculation semiquantitative score. Result: result showed tends better compared increase score group. Statistical test Man-Whitney confidence level 95% (p < 0,05) observation day sequentally p=0.100, p=0,100, p=0,700. Conclusion: applied benefits regarding eventhough there significant difference found statitistical test.